Convenient Access to α‐Amino‐ω‐Hydroxyl Heterobifunctional peg and ppo via a Sacrificial Hexahydro‐Triazine Star Strategy

Figure  2 for TrAz PEG

360

 and in Figure S7, Supporting Infor-

mation for TrAz PPO

85

. In the spectra every dot represents 

one assigned isotopic mass of the isotopic pattern of a polymer 

chain, as shown in a detailed manner in Figure S8, Supporting 

Information.

Acidic hydrolysis cleaves the hexahydro-triazine group into 

three parts as shown by Zhu and coworkers.

[16]

 In a similar pro-

cedure as reported by Pradipta et al. the cores of the star poly-

mers were hydrolyzed, using hydrochloric acid in methanol or 

ethanol.

[12]

 The resulting cleavage of the three aminal groups in 

the hexahydro triazine core leads to three linear PEG or PPO 

Macromol. Rapid Commun. 2019, 1900020

Scheme 1.  Synthesis strategy for 

α-amino-ω-hydroxyl heterobifunctional PEG.

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